We propose a deep survey of galaxies at 4.5 microns This wavelength is near the minimum of the local foreground emission where the DIRBE experiment aboard the Cosmic Background Explorer (COBE) will study the infrared background searching for the extragalactic background due to the redshifted emission of faint galaxies and protogalaxies. The proposed observations will be used in connection with the deep surveys done at longer wavelengths in the ISO central program and with the ground based surveys at shorter wavelengths (K band) for the interpretation of the DIRBE data. In the 3 to 6 microns wavelength range, the relative contributions of stars and the interstellar emission of very small particles for different types of galaxies is still an open question. The proposed survey will be necessary to remove (from the distant galaxies background) faint spiral and starburst galaxies at moderate redshifts for which the interstellar component could be dominant preventing a simple extrapolation from the K band surveys.