This solicited ISO open time proposal aims at building a complementary data base of ISO spectroscopic and imaging observations to study the thermal balance of dense and warm interstellar matter and the interaction of UV photons with molecular gas and dust in Photo-Dissociation Regions (PDRs). This proposal follows up the unexpected detection of the S(3) and S(5) v=0-0 lines of H2 in CVF observations of NGC 7023, M17 and two Ophiuchus PDRs. We propose to obtain (1) SWS and LWS spectra at positions selected on the basic of ISOCAM images and (2) CVF H2 images of targets already observed with the spectrometers.